A small molecule oligosaccharyltransferase inhibitor with pan-flaviviral activity

The mosquito-borne flaviviruses include important human pathogens such as dengue, Zika, West Nile and yellow fever virus, which pose a serious threat for global health. Recent genetic screens identified ER-membrane multiprotein complexes including the oligosaccharyltransferase (OST) complex as criti...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Puschnik, Andreas S., Marceau, Caleb D., Ooi, Yaw Shin, Majzoub, Karim, Rinis, Natalie, Contessa, Joseph N., Carette, Jan E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734657/
https://ncbi.nlm.nih.gov/pubmed/29241533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.054
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