Gene-environment induced epigenetic dynamics at rDNA in the mouse

Sub-optimal early life environments can influence life-long phenotypes, and epigenetic factors are thought to be key mediators of these effects. We show that early life protein restriction in mice induces a linear correlation between growth restriction and DNA methylation at a specific genetic varia...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Holland, Michelle L., Lowe, Robert, Caton, Paul W., Gemma, Carolina, Carbajosa, Guillermo, Danson, Amy F., Carpenter, Asha A. M., Loche, Elena, Ozanne, Susan E., Rakyan, Vardhman K.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734613/
https://ncbi.nlm.nih.gov/pubmed/27386920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf7040
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