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Correcting for cell-type composition bias in epigenome-wide association studies

Recent epigenome-wide association studies have indicated a potential role for epigenetic variation in the etiology of complex human diseases. However, one major challenge is to distinguish true epigenetic variation from changes caused by differences in cellular composition between the disease and no...

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Hlavní autoři: Lowe, Robert, Rakyan, Vardhman K
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062059/
https://ncbi.nlm.nih.gov/pubmed/25031617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm540
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