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Ras signaling in aging and metabolic regulation
Aberrant signal transduction downstream of the Ras GTPase has a well-established role in tumorigenesis. Mutations that result in hyperactivation of Ras are responsible for a third of all human cancers. Hence, small molecule inhibitors of the Ras signal transduction cascade have been under intense fo...
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| Veröffentlicht in: | Nutr Healthy Aging |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
IOS Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5734121/ https://ncbi.nlm.nih.gov/pubmed/29276789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/NHA-160021 |
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