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Tissue-specific Insulin Signaling in the Regulation of Metabolism and Aging
In mammals, insulin signaling regulates glucose homeostasis and plays an essential role in metabolism, organ growth, development, fertility, and lifespan. Defects in this signaling pathway contribute to various metabolic diseases such as type 2 diabetes, polycystic ovarian disease, hypertension, hyp...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140976/ https://ncbi.nlm.nih.gov/pubmed/25087968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1293 |
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