Oncogenic Role of THOR, a Conserved Cancer/Testis Long Noncoding RNA

Large scale transcriptome sequencing efforts have vastly expanded the catalog of long non-coding RNAs (lncRNAs) with varying evolutionary conservation, lineage expression, and cancer specificity. Here we functionally characterize a novel ultraconserved lncRNA, THOR (ENSG00000226856), which exhibits...

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Pubblicato in:Cell
Autori principali: Hosono, Yasuyuki, Niknafs, Yashar S, Prensner, John R, Iyer, Matthew K, Dhanasekaran, Saravana M, Mehra, Rohit, Pitchiaya, Sethuramasundaram, Tien, Jean, Escara-Wilke, June, Poliakov, Anton, Chu, Shih-Chun, Saleh, Sahal, Sankar, Keerthana, Su, Fengyun, Guo, Shuling, Qiao, Yuanyuan, Freier, Susan M, Bui, Huynh-Hoa, Cao, Xuhong, Malik, Rohit, Johnson, Timothy M, Beer, David G, Feng, Felix Y, Zhou, Weibin, Chinnaiyan, Arul M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734106/
https://ncbi.nlm.nih.gov/pubmed/29245011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.11.040
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