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Lateral hypothalamic neurotensin neurons orchestrate dual weight loss behaviors via distinct mechanisms

The central mechanism by which neurotensin (Nts) potentiates weight loss has remained elusive. We leveraged chemogenetics to reveal that Nts-expressing neurons of the lateral hypothalamic area (LHA) promote weight loss in mice by increasing volitional activity and restraining food intake. Intriguing...

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Publicat a:Cell Rep
Autors principals: Woodworth, Hillary L., Beekly, Bethany G., Batchelor, Hannah M., Bugescu, Raluca, Perez-Bonilla, Patricia, Schroeder, Laura E., Leinninger, Gina M.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734099/
https://ncbi.nlm.nih.gov/pubmed/29241540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.068
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