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Lateral hypothalamic neurotensin neurons orchestrate dual weight loss behaviors via distinct mechanisms

The central mechanism by which neurotensin (Nts) potentiates weight loss has remained elusive. We leveraged chemogenetics to reveal that Nts-expressing neurons of the lateral hypothalamic area (LHA) promote weight loss in mice by increasing volitional activity and restraining food intake. Intriguing...

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Podrobná bibliografie
Vydáno v:Cell Rep
Hlavní autoři: Woodworth, Hillary L., Beekly, Bethany G., Batchelor, Hannah M., Bugescu, Raluca, Perez-Bonilla, Patricia, Schroeder, Laura E., Leinninger, Gina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734099/
https://ncbi.nlm.nih.gov/pubmed/29241540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.068
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