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Lateral hypothalamic neurotensin neurons orchestrate dual weight loss behaviors via distinct mechanisms

The central mechanism by which neurotensin (Nts) potentiates weight loss has remained elusive. We leveraged chemogenetics to reveal that Nts-expressing neurons of the lateral hypothalamic area (LHA) promote weight loss in mice by increasing volitional activity and restraining food intake. Intriguing...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Woodworth, Hillary L., Beekly, Bethany G., Batchelor, Hannah M., Bugescu, Raluca, Perez-Bonilla, Patricia, Schroeder, Laura E., Leinninger, Gina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734099/
https://ncbi.nlm.nih.gov/pubmed/29241540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.068
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