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Lateral hypothalamic neurotensin neurons orchestrate dual weight loss behaviors via distinct mechanisms

The central mechanism by which neurotensin (Nts) potentiates weight loss has remained elusive. We leveraged chemogenetics to reveal that Nts-expressing neurons of the lateral hypothalamic area (LHA) promote weight loss in mice by increasing volitional activity and restraining food intake. Intriguing...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Woodworth, Hillary L., Beekly, Bethany G., Batchelor, Hannah M., Bugescu, Raluca, Perez-Bonilla, Patricia, Schroeder, Laura E., Leinninger, Gina M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734099/
https://ncbi.nlm.nih.gov/pubmed/29241540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.068
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