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Lateral hypothalamic neurotensin neurons orchestrate dual weight loss behaviors via distinct mechanisms

The central mechanism by which neurotensin (Nts) potentiates weight loss has remained elusive. We leveraged chemogenetics to reveal that Nts-expressing neurons of the lateral hypothalamic area (LHA) promote weight loss in mice by increasing volitional activity and restraining food intake. Intriguing...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Woodworth, Hillary L., Beekly, Bethany G., Batchelor, Hannah M., Bugescu, Raluca, Perez-Bonilla, Patricia, Schroeder, Laura E., Leinninger, Gina M.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734099/
https://ncbi.nlm.nih.gov/pubmed/29241540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.068
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