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A Novel Series of Enoyl Reductase Inhibitors Targeting the ESKAPE Pathogens, Staphylococcus aureus and Acinetobacter baumannii

S. aureus and A. baumannii are among the ESKAPE pathogens that are increasingly difficult to treat due to the rise in the number of drug resistant strains. Novel therapeutics targeting these pathogens are much needed. The bacterial enoyl reductase (FabI) is as potentially significant drug target for...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Kwon, Jieun, Mistry, Tina, Ren, Jinhong, Johnson, Michael E., Mehboob, Shahila
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733704/
https://ncbi.nlm.nih.gov/pubmed/29162308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.11.018
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