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Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage

Disturbances in redox equilibrium in tissue can lead to inflammatory state, which is a mediatory factor in many human diseases. The mechanism(s) by which exogenous oxidants may activate an inflammatory response is not fully understood. Emerging evidence suggest that oxidant-induced Toll-like recepto...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Zhang, Yan, Igwe, Orisa J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733690/
https://ncbi.nlm.nih.gov/pubmed/29175419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.11.012
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