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Activation of c-Src: A hub for exogenous prooxidant-induced activation of Toll-like receptor 4 signaling ()

To study the role of c-Src kinase in prooxidant-induced stimulation of TLR4, we used LPS-EK and MPLA as TLR4 specific agonists and positive controls, and SIN-1 and PPC as prooxidant sources. We used HEK-Blue mTLR4 cell line that is stably transfected with mouse TLR4 and that expresses optimized SEAP...

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Detalhes bibliográficos
Main Authors: Karki, Rajendra, Zhang, Yan, Igwe, Orisa J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037369/
https://ncbi.nlm.nih.gov/pubmed/24637265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.03.005
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