The TRPC1 Ca(2+)-permeable channel inhibits exercise-induced protection against high-fat diet-induced obesity and type II diabetes

The transient receptor potential canonical channel-1 (TRPC1) is a Ca(2+)-permeable channel found in key metabolic organs and tissues, including the hypothalamus, adipose tissue, and skeletal muscle. Loss of TRPC1 may alter the regulation of cellular energy metabolism resulting in insulin resistance...

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Опубликовано в: :J Biol Chem
Главные авторы: Krout, Danielle, Schaar, Anne, Sun, Yuyang, Sukumaran, Pramod, Roemmich, James N., Singh, Brij B., Claycombe-Larson, Kate J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2017
Предметы:
Metabolism
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733613/
https://ncbi.nlm.nih.gov/pubmed/29074621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809954
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