Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex

Transcription factor 19 (TCF19) has been reported as a type 1 diabetes–associated locus involved in maintenance of pancreatic β cells through a fine-tuned regulation of cell proliferation and apoptosis. TCF19 also exhibits genomic association with type 2 diabetes, although the precise molecular mech...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Sen, Sabyasachi, Sanyal, Sulagna, Srivastava, Dushyant Kumar, Dasgupta, Dipak, Roy, Siddhartha, Das, Chandrima
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733577/
https://ncbi.nlm.nih.gov/pubmed/29042441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786863
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