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Effect of Flavin-Containing Monooxygenase Genotype, Mouse Strain, and Gender on Trimethylamine N-oxide Production, Plasma Cholesterol Concentration, and an Index of Atherosclerosis

The objectives of the study were to determine the contribution, in mice, of members of the flavin-containing monooxygenase (FMO) family to the production of trimethylamine (TMA) N-oxide (TMAO), a potential proatherogenic molecule, and whether under normal dietary conditions differences in TMAO produ...

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Bibliografiske detaljer
Udgivet i:Drug Metab Dispos
Main Authors: Veeravalli, Sunil, Karu, Kersti, Scott, Flora, Fennema, Diede, Phillips, Ian R., Shephard, Elizabeth A.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733448/
https://ncbi.nlm.nih.gov/pubmed/29070510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.077636
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