Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver

BACKGROUND & AIMS: Hepatitis B virus (HBV) infects hepatocytes, but the mechanisms of the immune response against the virus and how it affects disease progression are unclear. METHODS: We performed studies with BALB/c Rag2(–/–)Il2rg(–/–)Sirpa(NOD)Alb-uPA(tg/tg) mice, stably engrafted with human...

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Publicado no:Gastroenterology
Main Authors: Dusséaux, Mathilde, Masse-Ranson, Guillemette, Darche, Sylvie, Ahodantin, James, Li, Yan, Fiquet, Oriane, Beaumont, Elodie, Moreau, Pierrick, Rivière, Lise, Neuveut, Christine, Soussan, Patrick, Roingeard, Philippe, Kremsdorf, Dina, Di Santo, James P., Strick-Marchand, Helene
Formato: Artigo
Idioma:Inglês
Publicado em: W.B. Saunders 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733397/
https://ncbi.nlm.nih.gov/pubmed/28851562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.08.034
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