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Salidroside Inhibits HMGB1 Acetylation and Release through Upregulation of SirT1 during Inflammation

HMGB1, a highly conserved nonhistone DNA-binding protein, plays an important role in inflammatory diseases. Once released to the extracellular space, HMGB1 acts as a proinflammatory cytokine that triggers inflammatory reaction. Our previous study showed that salidroside exerts anti-inflammatory effe...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Qi, Zhilin, Zhang, Yao, Qi, Shimei, Ling, Liefeng, Gui, Lin, Yan, Liang, Lv, Jun, Li, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733170/
https://ncbi.nlm.nih.gov/pubmed/29333216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9821543
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