Autocrine hGH stimulates oncogenicity, epithelial-mesenchymal transition and cancer stem cell-like behavior in human colorectal carcinoma

Tumor derived human growth hormone (hGH) has been implicated in cancer development and progression. However, the specific functional role of autocrine/paracrine hGH in colorectal cancer (CRC) remains largely to be determined. Herein, we demonstrated a crucial oncogenic role of autocrine hGH in CRC p...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Wang, Jing-Jing, Chong, Qing-Yun, Sun, Xin-Bao, You, Ming-Liang, Pandey, Vijay, Chen, Yi-Jun, Zhuang, Qiu-Shi, Liu, Dong-Xu, Ma, Lan, Wu, Zheng-Sheng, Zhu, Tao, Lobie, Peter E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732775/
https://ncbi.nlm.nih.gov/pubmed/29262609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21812
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