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Reversion of resistance to oxaliplatin by inhibition of p38 MAPK in colorectal cancer cell lines: involvement of the calpain / Nox1 pathway

Oxaliplatin is a major treatment for metastatic colorectal cancer, however its effectiveness is greatly diminished by the development of resistances. Our previous work has shown that oxaliplatin efficacy depends on the reactive oxygen species (ROS) produced by Nox1. In this report, we investigated N...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Chocry, Mathieu, Leloup, Ludovic, Kovacic, Hervé
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732761/
https://ncbi.nlm.nih.gov/pubmed/29262595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21780
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