Reprogramming of leukemic cell metabolism through the naphthoquinonic compound Quambalarine B

Abnormalities in cancer metabolism represent potential targets for cancer therapy. We have recently identified a natural compound Quambalarine B (QB), which inhibits proliferation of several leukemic cell lines followed by cell death. We have predicted ubiquinone binding sites of mitochondrial respi...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Vališ, Karel, Grobárová, Valéria, Hernychová, Lucie, Bugáňová, Martina, Kavan, Daniel, Kalous, Martin, Černý, Jiří, Stodůlková, Eva, Kuzma, Marek, Flieger, Miroslav, Černý, Jan, Novák, Petr
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732718/
https://ncbi.nlm.nih.gov/pubmed/29262552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21663
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