Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma

SOX2 is a transcription factor essential for early mammalian development and for the maintenance of stem cells. Recently, SOX2 was identified as a lineage specific oncogene, recurrently amplified and activated in lung and esophageal squamous cell carcinoma (SCC). In this study, we have developed a z...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yokota, Etsuko, Yamatsuji, Tomoki, Takaoka, Munenori, Haisa, Minoru, Takigawa, Nagio, Miyake, Noriko, Ikeda, Tomoko, Mori, Tomoaki, Ohno, Serika, Sera, Takashi, Fukazawa, Takuya, Naomoto, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732711/
https://ncbi.nlm.nih.gov/pubmed/29262545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21523
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