SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma

Since the SOX2 amplification was identified in lung squamous cell carcinoma (lung SCC), SOX2 transcriptional downstream targets have been actively investigated; however, such targets are often cell line specific. Here, in order to identify highly consensus SOX2 downstream genes in lung SCC cells, we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fukazawa, Takuya, Guo, Minzhe, Ishida, Naomasa, Yamatsuji, Tomoki, Takaoka, Munenori, Yokota, Etsuko, Haisa, Minoru, Miyake, Noriko, Ikeda, Tomoko, Okui, Tatsuo, Takigawa, Nagio, Maeda, Yutaka, Naomoto, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742851/
https://ncbi.nlm.nih.gov/pubmed/26846300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20113
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