SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma

Since the SOX2 amplification was identified in lung squamous cell carcinoma (lung SCC), SOX2 transcriptional downstream targets have been actively investigated; however, such targets are often cell line specific. Here, in order to identify highly consensus SOX2 downstream genes in lung SCC cells, we...

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Vydáno v:Sci Rep
Hlavní autoři: Fukazawa, Takuya, Guo, Minzhe, Ishida, Naomasa, Yamatsuji, Tomoki, Takaoka, Munenori, Yokota, Etsuko, Haisa, Minoru, Miyake, Noriko, Ikeda, Tomoko, Okui, Tatsuo, Takigawa, Nagio, Maeda, Yutaka, Naomoto, Yoshio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742851/
https://ncbi.nlm.nih.gov/pubmed/26846300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20113
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