Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis

The FGFR3-TACC3 fusion is an oncogenic driver in diverse malignancies, including bladder cancer, characterized by upregulated tyrosine kinase activity. To gain insights into distinct properties of FGFR3-TACC3 down-stream signalling, we utilised telomerase-immortalised normal human urothelial cell li...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lombardi, Benedetta, Ashford, Paul, Moya-Garcia, Aurelio A., Rust, Aleksander, Crawford, Mark, Williams, Sarah V., Knowles, Margaret A., Katan, Matilda, Orengo, Christine, Godovac-Zimmermann, Jasminka
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732698/
https://ncbi.nlm.nih.gov/pubmed/29262532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22048
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