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The use of the tyrosine kinase inhibitor Nilotinib in Spondyloarthritis: does targeting inflammatory pathways with a treatment lead to vascular toxicity?

Spondylarthritis (SpA) is an inflammatory rheumatic disease associated with increased incidence of major adverse cardiovascular events (MACEs). Recently, Paramarta et al. proposed the use of the tyrosine kinase inhibitor Nilotinib in Spondyloarthritis to target certain inflammatory pathways. However...

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Dades bibliogràfiques
Publicat a:J Transl Med
Autors principals: Omarjee, Loukman, Jaquinandi, Vincent, Mahe, Guillaume
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732514/
https://ncbi.nlm.nih.gov/pubmed/29246242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1334-1
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