The use of the tyrosine kinase inhibitor Nilotinib in Spondyloarthritis: does targeting inflammatory pathways with a treatment lead to vascular toxicity?

Spondylarthritis (SpA) is an inflammatory rheumatic disease associated with increased incidence of major adverse cardiovascular events (MACEs). Recently, Paramarta et al. proposed the use of the tyrosine kinase inhibitor Nilotinib in Spondyloarthritis to target certain inflammatory pathways. However...

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Bibliografische gegevens
Gepubliceerd in:J Transl Med
Hoofdauteurs: Omarjee, Loukman, Jaquinandi, Vincent, Mahe, Guillaume
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
Onderwerpen:
Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732514/
https://ncbi.nlm.nih.gov/pubmed/29246242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1334-1
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