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The use of the tyrosine kinase inhibitor Nilotinib in Spondyloarthritis: does targeting inflammatory pathways with a treatment lead to vascular toxicity?

Spondylarthritis (SpA) is an inflammatory rheumatic disease associated with increased incidence of major adverse cardiovascular events (MACEs). Recently, Paramarta et al. proposed the use of the tyrosine kinase inhibitor Nilotinib in Spondyloarthritis to target certain inflammatory pathways. However...

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Pubblicato in:J Transl Med
Autori principali: Omarjee, Loukman, Jaquinandi, Vincent, Mahe, Guillaume
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732514/
https://ncbi.nlm.nih.gov/pubmed/29246242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1334-1
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