Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes

The estrogen-related receptor (ERR) family of orphan nuclear receptor is composed of ERRα, ERRβ, and ERRγ, which are known to regulate various isoform-specific functions under normal and pathophysiological conditions. Here, we investigate the involvement of ERRs in the pathogenesis of osteoarthritis...

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Publicat a:Nat Commun
Autors principals: Son, Young-Ok, Park, Seulki, Kwak, Ji-Sun, Won, Yoonkyung, Choi, Wan-Su, Rhee, Jinseol, Chun, Churl-Hong, Ryu, Je-Hwang, Kim, Don-Kyu, Choi, Hueng-Sik, Chun, Jang-Soo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732273/
https://ncbi.nlm.nih.gov/pubmed/29247173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01868-8
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