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Lipopolysaccharide (LPS)-mediated priming of Toll-like receptor 4 enhances oxidant-induced prostaglandin E(2) biosynthesis in primary murine macrophages()

Agonists and pseudo-agonists for Toll-like receptor 4 (TLR4) are common in our environment. Thus, human exposure to these agents may result in “priming or sensitization” of TLR4. A body of evidence suggests that LPS-mediated sensitization of TLR4 can increase the magnitude of responses to exogenous...

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Detalhes bibliográficos
Publicado no:Int Immunopharmacol
Main Authors: Zhang, Yan, Igwe, Orisa J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732025/
https://ncbi.nlm.nih.gov/pubmed/29161659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2017.11.017
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