Novel allylated monocarbonyl analogs of curcumin induce mitotic arrest and apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and inhibition of STAT3

Curcumin is a promising active compound from a natural source and is extensively being tested in clinical trials because of its bio-functional properties. However, poor bioavailability has hampered its clinical application. Numerous attempts have been made in our laboratory to discover analogs of cu...

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Publicado en:Oncotarget
Autores principales: Rajamanickam, Vinothkumar, Zhu, Heping, Feng, Chen, Chen, Xi, Zheng, Hailun, Xu, Xiaohong, Zhang, Qianqian, Zou, Peng, He, Guodong, Dai, Xuanxuan, Yang, Xi, Wang, Yi, Liu, Zhiguo, Liang, Guang, Guo, Guilong
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731860/
https://ncbi.nlm.nih.gov/pubmed/29254150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20924
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