Role of sympathetic cotransmitter galanin on autonomic balance in heart failure: an active player or a bystander?

OBJECTIVE: Galanin, a cotransmitter similar to neuropeptide Y (NPY), aggravates autonomic imbalance in systolic heart failure (HF) by attenuating vagal tonus after burst sympathetic activity. In animal HF models, galanin antagonists have improved cardiac function. To determine whether galanin is a p...

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Vydáno v:Anatol J Cardiol
Hlavní autoři: Gür, Demet Özkaramanlı, Sağbaş, Miray, Akyüz, Aydın, Güzel, Savaş, Alpsoy, Şeref, Güler, Niyazi
Médium: Artigo
Jazyk:Inglês
Vydáno: Kare Publishing 2017
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Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731524/
https://ncbi.nlm.nih.gov/pubmed/28811392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14744/AnatolJCardiol.2017.7831
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