Role of sympathetic cotransmitter galanin on autonomic balance in heart failure: an active player or a bystander?

OBJECTIVE: Galanin, a cotransmitter similar to neuropeptide Y (NPY), aggravates autonomic imbalance in systolic heart failure (HF) by attenuating vagal tonus after burst sympathetic activity. In animal HF models, galanin antagonists have improved cardiac function. To determine whether galanin is a p...

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Bibliographic Details
Published in:Anatol J Cardiol
Main Authors: Gür, Demet Özkaramanlı, Sağbaş, Miray, Akyüz, Aydın, Güzel, Savaş, Alpsoy, Şeref, Güler, Niyazi
Format: Artigo
Language:Inglês
Published: Kare Publishing 2017
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Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731524/
https://ncbi.nlm.nih.gov/pubmed/28811392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14744/AnatolJCardiol.2017.7831
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