Both Sphingomyelin and Cholesterol in the Host Cell Membrane Are Essential for Rubella Virus Entry

Rubella virus (RuV) causes a systemic infection, and transplacental fetal infection causes congenital rubella syndrome. In this study, we showed that treatment of cells with sphingomyelinase inhibited RuV infection. Assays using inhibitors of serine palmitoyl transferase and ceramide transport prote...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Otsuki, Noriyuki, Sakata, Masafumi, Saito, Kyoko, Okamoto, Kiyoko, Mori, Yoshio, Hanada, Kentaro, Takeda, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730775/
https://ncbi.nlm.nih.gov/pubmed/29070689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01130-17
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