Both Sphingomyelin and Cholesterol in the Host Cell Membrane Are Essential for Rubella Virus Entry

Rubella virus (RuV) causes a systemic infection, and transplacental fetal infection causes congenital rubella syndrome. In this study, we showed that treatment of cells with sphingomyelinase inhibited RuV infection. Assays using inhibitors of serine palmitoyl transferase and ceramide transport prote...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Otsuki, Noriyuki, Sakata, Masafumi, Saito, Kyoko, Okamoto, Kiyoko, Mori, Yoshio, Hanada, Kentaro, Takeda, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730775/
https://ncbi.nlm.nih.gov/pubmed/29070689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01130-17
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