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Both Sphingomyelin and Cholesterol in the Host Cell Membrane Are Essential for Rubella Virus Entry

Rubella virus (RuV) causes a systemic infection, and transplacental fetal infection causes congenital rubella syndrome. In this study, we showed that treatment of cells with sphingomyelinase inhibited RuV infection. Assays using inhibitors of serine palmitoyl transferase and ceramide transport prote...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Otsuki, Noriyuki, Sakata, Masafumi, Saito, Kyoko, Okamoto, Kiyoko, Mori, Yoshio, Hanada, Kentaro, Takeda, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730775/
https://ncbi.nlm.nih.gov/pubmed/29070689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01130-17
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