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Mutations in the Influenza A Virus M1 Protein Enhance Virus Budding To Complement Lethal Mutations in the M2 Cytoplasmic Tail

The influenza A virus M1 and M2 proteins play important roles in virus assembly and in the morphology of virus particles. Mutations in the distal cytoplasmic tail region of M2, and in particular a tyrosine-to-alanine mutation at residue 76 (Y76A), were essential for infectious virus production and f...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Liu, Hsuan, Grantham, Michael L., Pekosz, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730759/
https://ncbi.nlm.nih.gov/pubmed/29046451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00858-17
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