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Tyrosines in the Influenza A Virus M2 Protein Cytoplasmic Tail Are Critical for Production of Infectious Virus Particles

The cytoplasmic tail of the influenza A virus M2 protein is required for the production of infectious virions. In this study, critical residues in the M2 cytoplasmic tail were identified by single-alanine scanning mutagenesis. The tyrosine residue at position 76, which is conserved in >99% of inf...

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Autori principali: Grantham, Michael L., Stewart, Shaun M., Lalime, Erin N., Pekosz, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918991/
https://ncbi.nlm.nih.gov/pubmed/20573832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00853-10
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