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Signaling of the Complement Cleavage Product Anaphylatoxin C5a Through C5aR (CD88) Contributes to Pharmacological Hematopoietic Stem Cell Mobilization

Several mechanisms have been postulated for orchestrating the mobilization of hematopoietic stem/progenitor cells (HSPCs), and we previously proposed that activation of the complement cascade plays a crucial role in the initiation and execution of the egress of HSPCs from bone marrow (BM) into perip...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Rev
Hauptverfasser: Bujko, Kamila, Rzeszotek, Sylwia, Hoehlig, Kai, Yan, Jun, Vater, Axel, Ratajczak, Mariusz Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730632/
https://ncbi.nlm.nih.gov/pubmed/28918528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-017-9769-6
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