Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis

Complement activation, an integral arm of innate immunity, may be the critical link to the pathogenesis of idiopathic pulmonary fibrosis (IPF). Whereas we have previously reported elevated anaphylatoxins—complement component 3a (C3a) and complement component 5a (C5a)—in IPF, which interact with TGF-...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Gu, Hongmei, Fisher, Amanda J., Mickler, Elizabeth A., Duerson, Frank, Cummings, Oscar W., Peters-Golden, Marc, Twigg, Homer L., Woodruff, Trent M., Wilkes, David S., Vittal, Ragini
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4871799/
https://ncbi.nlm.nih.gov/pubmed/26956419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500044
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