CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity

Insulin plays a major role in glucose metabolism and insulin-signaling defects are present in obesity and diabetes. CK2 is a pleiotropic protein kinase implicated in fundamental cellular pathways and abnormally elevated in tumors. Here we report that in human and murine adipocytes CK2-inhibition dec...

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Published in:Sci Rep
Main Authors: Borgo, Christian, Milan, Gabriella, Favaretto, Francesca, Stasi, Fabio, Fabris, Roberto, Salizzato, Valentina, Cesaro, Luca, Belligoli, Anna, Sanna, Marta, Foletto, Mirto, Prevedello, Luca, Vindigni, Vincenzo, Bardini, Romeo, Donella-Deana, Arianna, Vettor, Roberto
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730587/
https://ncbi.nlm.nih.gov/pubmed/29242563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17809-w
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