Phase I Clinical Trial of Lenalidomide in Combination with Sorafenib in Patients with Advanced Cancer

BACKGROUND: Preclinical data have shown that lenalidomide and sorafenib target endothelial cells, inhibiting growth of ocular melanoma cells in a xenograft model. We conducted a Phase I study of lenalidomide and sorafenib in patients with advanced cancer. METHODS: During the escalation phase, lenali...

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Detalhes bibliográficos
Publicado no:Invest New Drugs
Main Authors: Ganesan, Prasanth, Piha-Paul, Sarina, Naing, Aung, Falchook, Gerald, Wheler, Jennifer, Fu, Siqing, Hong, David S., Kurzrock, Razelle, Janku, Filip, Laday, Shell, Bedikian, Agop Y., Kies, Merrill, Wolff, Robert A., Tsimberidou, Apostolia M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730367/
https://ncbi.nlm.nih.gov/pubmed/23756764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-9966-3
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