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Phase I Clinical Trial of Lenalidomide in Combination with Sorafenib in Patients with Advanced Cancer
BACKGROUND: Preclinical data have shown that lenalidomide and sorafenib target endothelial cells, inhibiting growth of ocular melanoma cells in a xenograft model. We conducted a Phase I study of lenalidomide and sorafenib in patients with advanced cancer. METHODS: During the escalation phase, lenali...
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| Veröffentlicht in: | Invest New Drugs |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5730367/ https://ncbi.nlm.nih.gov/pubmed/23756764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-9966-3 |
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