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Non-immune cells equipped with T cell receptor-like signaling for cancer cell ablation
The ability to engineer custom cell-contact-sensing output devices into human non-immune cells would be useful for extending the applicability of cell-based cancer therapies and avoiding risks associated with engineered immune cells. Here, we have developed a new class of synthetic T-cell receptor-l...
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| Udgivet i: | Nat Chem Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5730048/ https://ncbi.nlm.nih.gov/pubmed/29131143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2498 |
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