Ailanthone inhibits non-small cell lung cancer cell growth through repressing DNA replication via downregulating RPA1

BACKGROUND: The identification of bioactive compounds from Chinese medicine plays a crucial role in the development of novel reagents against non-small lung cancer (NSCLC). METHODS: High throughput screening assay and analyses of cell growth, cell cycle, apoptosis, cDNA microarray, BrdU incorporatio...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Ni, Zhongya, Yao, Chao, Zhu, Xiaowen, Gong, Chenyuan, Xu, Zihang, Wang, Lixin, Li, Suyun, Zou, Chunpu, Zhu, Shiguo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
Subjects:
Translational Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729430/
https://ncbi.nlm.nih.gov/pubmed/29024939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.319
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