Rocaglamide enhances NK cell-mediated killing of non-small cell lung cancer cells by inhibiting autophagy

Targeting macroautophagy/autophagy is a novel strategy in cancer immunotherapy. In the present study, we showed that the natural product rocaglamide (RocA) enhanced natural killer (NK) cell-mediated lysis of non-small cell lung cancer (NSCLC) cells in vitro and tumor regression in vivo. Moreover, th...

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Udgivet i:Autophagy
Main Authors: Yao, Chao, Ni, Zhongya, Gong, Chenyuan, Zhu, Xiaowen, Wang, Lixin, Xu, Zihang, Zhou, Chunxian, Li, Suyun, Zhou, Wuxiong, Zou, Chunpu, Zhu, Shiguo
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper - Translational
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135631/
https://ncbi.nlm.nih.gov/pubmed/29969944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1489946
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