Sex-Specific Effects of the Huntington Gene on Normal Neurodevelopment

Huntington disease is a neurodegenerative disorder caused by a gene (HTT) with a unique feature of trinucleotide repeats ranging from 10 to 35 in healthy people; when expanded beyond 39 repeats, Huntington disease develops. Animal models demonstrate that HTT is vital to brain development; however, t...

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Pubblicato in:J Neurosci Res
Autori principali: Lee, Jessica K., Ding, Yue, Conrad, Amy L., Cattaneo, Elena, Epping, Eric, Mathews, Kathy, Gonzalez-Alegre, Pedro, Cahill, Larry, Magnotta, Vincent, Schlaggar, Bradley L., Perlmutter, Joel S., Kim, Regina E.Y., Dawson, Jeffrey D., Nopoulos, Peg
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729280/
https://ncbi.nlm.nih.gov/pubmed/27870408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23980
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