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Opposing post-transcriptional control of InR by FMRP and LIN-28 adjusts stem cell based tissue growth

Although the intrinsic mechanisms that control whether stem cells divide symmetrically or asymmetrically underlie tissue growth and homeostasis, they remain poorly defined. We report that the RNA-binding protein, Fragile X Mental Retardation Protein (FMRP), limits the symmetric division, and resulti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: Luhur, Arthur, Buddika, Kasun, Ariyapala, Ishara Surangi, Chen, Shengyao, Sokol, Nicholas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728658/
https://ncbi.nlm.nih.gov/pubmed/29212015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.039
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