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Opposing post-transcriptional control of InR by FMRP and LIN-28 adjusts stem cell based tissue growth

Although the intrinsic mechanisms that control whether stem cells divide symmetrically or asymmetrically underlie tissue growth and homeostasis, they remain poorly defined. We report that the RNA-binding protein, Fragile X Mental Retardation Protein (FMRP), limits the symmetric division, and resulti...

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Detalles Bibliográficos
Publicado en:Cell Rep
Autores principales: Luhur, Arthur, Buddika, Kasun, Ariyapala, Ishara Surangi, Chen, Shengyao, Sokol, Nicholas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728658/
https://ncbi.nlm.nih.gov/pubmed/29212015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.039
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