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Checkpoint blockade in Hodgkin and non-Hodgkin lymphoma
Classical Hodgkin lymphoma (cHL) is characterized by nearly universal genetic alterations in 9p24.1, resulting in constitutive expression of PD-1 ligands. This likely underlies the unique sensitivity of cHL to PD-1 blockade, with response rates of ∼70% in relapsed/refractory disease. There are now n...
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| Vydáno v: | Blood Adv |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728646/ https://ncbi.nlm.nih.gov/pubmed/29296917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017012534 |
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