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Checkpoint blockade in Hodgkin and non-Hodgkin lymphoma
Classical Hodgkin lymphoma (cHL) is characterized by nearly universal genetic alterations in 9p24.1, resulting in constitutive expression of PD-1 ligands. This likely underlies the unique sensitivity of cHL to PD-1 blockade, with response rates of ∼70% in relapsed/refractory disease. There are now n...
Gardado en:
| Publicado en: | Blood Adv |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728646/ https://ncbi.nlm.nih.gov/pubmed/29296917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017012534 |
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