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Checkpoint blockade in Hodgkin and non-Hodgkin lymphoma

Classical Hodgkin lymphoma (cHL) is characterized by nearly universal genetic alterations in 9p24.1, resulting in constitutive expression of PD-1 ligands. This likely underlies the unique sensitivity of cHL to PD-1 blockade, with response rates of ∼70% in relapsed/refractory disease. There are now n...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Merryman, Reid W., Armand, Philippe, Wright, Kyle T., Rodig, Scott J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728646/
https://ncbi.nlm.nih.gov/pubmed/29296917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017012534
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