Bone marrow transplantation prevents right ventricle disease in the caveolin-1–deficient mouse model of pulmonary hypertension

Accumulating evidence shows a causative role for the bone marrow (BM) in the genesis and progression of pulmonary hypertension (PH). Engraftment of BM hematopoietic stem cells from PH patients to mice reproduces the cardiopulmonary pathology of PH. However, it is unknown whether healthy BM can preve...

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Vydáno v:Blood Adv
Hlavní autoři: Asosingh, Kewal, Wanner, Nicholas, Weiss, Kelly, Queisser, Kimberly, Gebreab, Liya, Kassa, Biruk, Stuehr, Eric, Graham, Brian, Erzurum, Serpil
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2017
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728598/
https://ncbi.nlm.nih.gov/pubmed/29296972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016002691
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