Bone marrow transplantation prevents right ventricle disease in the caveolin-1–deficient mouse model of pulmonary hypertension

Accumulating evidence shows a causative role for the bone marrow (BM) in the genesis and progression of pulmonary hypertension (PH). Engraftment of BM hematopoietic stem cells from PH patients to mice reproduces the cardiopulmonary pathology of PH. However, it is unknown whether healthy BM can preve...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Asosingh, Kewal, Wanner, Nicholas, Weiss, Kelly, Queisser, Kimberly, Gebreab, Liya, Kassa, Biruk, Stuehr, Eric, Graham, Brian, Erzurum, Serpil
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728598/
https://ncbi.nlm.nih.gov/pubmed/29296972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016002691
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