Whole-exome sequencing in evaluation of patients with venous thromboembolism

Genetics play a significant role in venous thromboembolism (VTE), yet current clinical laboratory-based testing identifies a known heritable thrombophilia (factor V Leiden, prothrombin gene mutation G20210A, or a deficiency of protein C, protein S, or antithrombin) in only a minority of VTE patients...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Lee, Eun-Ju, Dykas, Daniel J., Leavitt, Andrew D., Camire, Rodney M., Ebberink, Eduard, García de Frutos, Pablo, Gnanasambandan, Kavitha, Gu, Sean X., Huntington, James A., Lentz, Steven R., Mertens, Koen, Parish, Christopher R., Rezaie, Alireza R., Sayeski, Peter P., Cromwell, Caroline, Bar, Noffar, Halene, Stephanie, Neparidze, Natalia, Parker, Terri L., Burns, Adrienne J., Dumont, Anne, Yao, Xiaopan, Chaar, Cassius Iyad Ochoa, Connors, Jean M., Bale, Allen E., Lee, Alfred Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728544/
https://ncbi.nlm.nih.gov/pubmed/29296762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017005249
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