The soluble mannose receptor (sMR) is elevated in alcoholic liver disease and associated with disease severity, portal hypertension, and mortality in cirrhosis patients

BACKGROUND AND AIMS: Hepatic macrophages (Kupffer cells) are involved in the immunopathology of alcoholic liver disease (ALD). The mannose receptor (MR, CD206), expressed primarily by macrophages, mediates endocytosis, antigen presentation and T-cell activation. A soluble form, sMR, has recently bee...

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Pubblicato in:PLoS One
Autori principali: Sandahl, Thomas Damgaard, Støy, Sidsel Hyldgaard, Laursen, Tea Lund, Rødgaard-Hansen, Sidsel, Møller, Holger Jon, Møller, Søren, Vilstrup, Hendrik, Grønbæk, Henning
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728513/
https://ncbi.nlm.nih.gov/pubmed/29236785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189345
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